Growth Hormone

    Last Updated: April 29, 2017

    Growth hormone (GH) is a peptide hormone that regulates growth in youth, and in adults is thought to promote fat loss and longevity. Increasing growth hormone should improve these goals, but supplements are currently lacklustre.

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    Examine Database: Growth Hormone

    C
    Mixed effect
    C
    Mixed effect
    D
    No effect
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    Examine Database References

    1. Pyridoxine (Vitamin B6) - C Barletta, M Sellini, A Bartoli, C Bigi, R Buzzetti, C Giovannini[Influence of administration of pyridoxine on circadian rhythm of plasma ACTH, cortisol prolactin and somatotropin in normal subjects]Boll Soc Ital Biol Sper.(1984 Feb 28)
    2. Melatonin - Kostoglou-Athanassiou I, Treacher DF, Wheeler MJ, Forsling MLMelatonin administration and pituitary hormone secretionClin Endocrinol (Oxf).(1998 Jan)
    3. OMAD And 20:4 Intermittent Fasting - B D Horne, J B Muhlestein, D L Lappé, H T May, J F Carlquist, O Galenko, K D Brunisholz, J L AndersonRandomized cross-over trial of short-term water-only fasting: metabolic and cardiovascular consequencesNutr Metab Cardiovasc Dis.(2013 Nov)
    4. DHEA - Libè R, Barbetta L, Dall'Asta C, Salvaggio F, Gala C, Beck-Peccoz P, Ambrosi BEffects of dehydroepiandrosterone (DHEA) supplementation on hormonal, metabolic and behavioral status in patients with hypoadrenalismJ Endocrinol Invest.(2004 Sep)
    5. Alanylglutamine - Hoffman JR, Ratamess NA, Kang J, Rashti SL, Kelly N, Gonzalez AM, Stec M, Anderson S, Bailey BL, Yamamoto LM, Hom LL, Kupchak BR, Faigenbaum AD, Maresh CMExamination of the efficacy of acute L-alanyl-L-glutamine ingestion during hydration stress in endurance exerciseJ Int Soc Sports Nutr.(2010 Feb 3)
    6. Beta-Alanine - Hoffman J, Ratamess NA, Ross R, Kang J, Magrelli J, Neese K, Faigenbaum AD, Wise JABeta-alanine and the hormonal response to exerciseInt J Sports Med.(2008 Dec)
    7. Ketogenic Diet - Boden G, Sargrad K, Homko C, Mozzoli M, Stein TPEffect of a low-carbohydrate diet on appetite, blood glucose levels, and insulin resistance in obese patients with type 2 diabetesAnn Intern Med.(2005 Mar 15)
    8. Citrulline - Sureda A, Córdova A, Ferrer MD, Pérez G, Tur JA, Pons AL-citrulline-malate influence over branched chain amino acid utilization during exerciseEur J Appl Physiol.(2010 Sep)
    9. Arginine - Collier SR, Casey DP, Kanaley JAGrowth hormone responses to varying doses of oral arginineGrowth Horm IGF Res.(2005 Apr)
    10. Arginine - Abel T, Knechtle B, Perret C, Eser P, von Arx P, Knecht HInfluence of chronic supplementation of arginine aspartate in endurance athletes on performance and substrate metabolism - a randomized, double-blind, placebo-controlled studyInt J Sports Med.(2005 Jun)
    11. Melatonin - Forsling ML, Wheeler MJ, Williams AJThe effect of melatonin administration on pituitary hormone secretion in manClin Endocrinol (Oxf).(1999 Nov)
    12. Arginine - Isidori A, Lo Monaco A, Cappa MA study of growth hormone release in man after oral administration of amino acidsCurr Med Res Opin.(1981)
    13. Rhodiola Rosea - Jówko E, Sadowski J, Długołęcka B, Gierczuk D, Opaszowski B, Cieśliński IEffects of Rhodiola rosea supplementation on mental performance, physical capacity, and oxidative stress biomarkers in healthy menJ Sport Health Sci.(2018 Oct)
    14. Creatine - D. Sheikholeslami Vatania, H. Farajib, R. Sooric, M. MogharnasidThe effects of creatine supplementation on performance and hormonal response in amateur swimmersScience and Sports.()
    15. Alpha-GPC - Tim Ziegenfuss, Jamie Landis and Jennifer HofheinsAcute supplementation with alpha-glycerylphosphorylcholine augments growth hormone response to, and peak force production during, resistance exerciseJISSN.()
    16. Phosphatidylserine - Monteleone P, Maj M, Beinat L, Natale M, Kemali DBlunting by chronic phosphatidylserine administration of the stress-induced activation of the hypothalamo-pituitary-adrenal axis in healthy menEur J Clin Pharmacol.(1992)
    17. Velvet Antler - Syrotuik DG, MacFadyen KL, Harber VJ, Bell GJEffect of elk velvet antler supplementation on the hormonal response to acute and chronic exercise in male and female rowersInt J Sport Nutr Exerc Metab.(2005 Aug)
    18. Nicotine - Morgan TM, Crawford L, Stoller A, Toth D, Yeo KT, Baron JAAcute effects of nicotine on serum glucose insulin growth hormone and cortisol in healthy smokersMetabolism.(2004 May)
    19. Betaine - Apicella JM, Lee EC, Bailey BL, Saenz C, Anderson JM, Craig SA, Kraemer WJ, Volek JS, Maresh CMBetaine supplementation enhances anabolic endocrine and Akt signaling in response to acute bouts of exerciseEur J Appl Physiol.(2013 Mar)
    20. Alcohol - M Välimäki, J A Tuominen, I Huhtaniemi, R YlikahriThe pulsatile secretion of gonadotropins and growth hormone, and the biological activity of luteinizing hormone in men acutely intoxicated with ethanolAlcohol Clin Exp Res.(1990 Dec)
    21. DHEA - Alessandro D Genazzani, Massimo Stomati, Francesca Bernardi, Matteo Pieri, Lucio Rovati, Andrea R GenazzaniLong-term low-dose dehydroepiandrosterone oral supplementation in early and late postmenopausal women modulates endocrine parameters and synthesis of neuroactive steroidsFertil Steril.(2003 Dec)
    22. Creatine - Schedel JM, Tanaka H, Kiyonaga A, Shindo M, Schutz YAcute creatine loading enhances human growth hormone secretionJ Sports Med Phys Fitness.(2000 Dec)
    23. Vitamin D - Amirhossein Ramezani Ahmadi, Majid Mohammadshahi, Aliakbar Alizadeh, Kambiz Ahmadi Angali, Alireza JahanshahiEffects of vitamin D3 supplementation for 12 weeks on serum levels of anabolic hormones, anaerobic power, and aerobic performance in active male subjects: A randomized, double-blind, placebo-controlled trialEur J Sport Sci.(2020 Nov)
    24. Arginine - Marcell TJ, Taaffe DR, Hawkins SA, Tarpenning KM, Pyka G, Kohlmeier L, Wiswell RA, Marcus ROral arginine does not stimulate basal or augment exercise-induced GH secretion in either young or old adultsJ Gerontol A Biol Sci Med Sci.(1999 Aug)
    25. Colostrum - A Mero, H Miikkulainen, J Riski, R Pakkanen, J Aalto, T TakalaEffects of bovine colostrum supplementation on serum IGF-I, IgG, hormone, and saliva IgA during trainingJ Appl Physiol (1985).(1997 Oct)
    26. Citrulline - C Moinard, I Nicolis, N Neveux, S Darquy, S Bénazeth, L CynoberDose-ranging effects of citrulline administration on plasma amino acids and hormonal patterns in healthy subjects: the Citrudose pharmacokinetic studyBr J Nutr.(2008 Apr)
    27. Creatine - Peyrebrune MC, Stokes K, Hall GM, Nevill MEEffect of creatine supplementation on training for competition in elite swimmersMed Sci Sports Exerc.(2005 Dec)
    28. Pyridoxine (Vitamin B6) - C Moretti, A Fabbri, L Gnessi, V Bonifacio, F Fraioli, A IsidoriPyridoxine (B6) suppresses the rise in prolactin and increases the rise in growth hormone induced by exerciseN Engl J Med.(1982 Aug 12)
    29. Gamma Oryzanol - Fry AC, Bonner E, Lewis DL, Johnson RL, Stone MH, Kraemer WJThe effects of gamma-oryzanol supplementation during resistance exercise trainingInt J Sport Nutr.(1997 Dec)
    30. Creatine - Schilling BK, Stone MH, Utter A, Kearney JT, Johnson M, Coglianese R, Smith L, O'Bryant HS, Fry AC, Starks M, Keith R, Stone MECreatine supplementation and health variables: a retrospective studyMed Sci Sports Exerc.(2001 Feb)
    31. HMB - Portal S, Zadik Z, Rabinowitz J, Pilz-Burstein R, Adler-Portal D, Meckel Y, Cooper DM, Eliakim A, Nemet DThe effect of HMB supplementation on body composition, fitness, hormonal and inflammatory mediators in elite adolescent volleyball players: a prospective randomized, double-blind, placebo-controlled studyEur J Appl Physiol.(2011 Sep)
    32. Alpha-GPC - Kawamura T, Okubo T, Sato K, Fujita S, Goto K, Hamaoka T, Iemitsu MGlycerophosphocholine enhances growth hormone secretion and fat oxidation in young adultsNutrition.(2012 Jun 5)
    33. Coenzyme Q10 - Tianqing Zhang, Qi He, Hao Xiu, ZiZhu Zhang, Yao Liu, Zhenrong Chen, Hengjing HuEfficacy and Safety of Coenzyme Q10 Supplementation in the Treatment of Polycystic Ovary Syndrome: a Systematic Review and Meta-analysisReprod Sci.(2022 Aug 8)