Peripheral Vascular Disease Symptoms

    Last Updated: August 16, 2022

    Peripheral vascular disease is narrowing of the blood vessels outside the heart due to atherosclerosis. Many people do not experience symptoms, but common symptoms include leg/foot pain, pale or bluish skin color, reduced leg hair, and lower body wounds that won't heal.

    examine-databaseExamine Database
    253 participants in 6 trials

    Examine Database: Peripheral Vascular Disease Symptoms

    Garlic
    D
    No effect
    Cocoa Extract
    C
    Small Improvement
    L-Carnitine
    B
    Small Improvement
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    Examine Database References

    1. Cocoa Extract - Hammer A, Koppensteiner R, Steiner S, Niessner A, Goliasch G, Gschwandtner M, Hoke MDark chocolate and vascular function in patients with peripheral artery disease: a randomized, controlled cross-over trialClin Hemorheol Microcirc.(2015)
    2. Garlic - Kiesewetter H, Jung F, Jung EM, Blume J, Mrowietz C, Birk A, Koscielny J, Wenzel EEffects of garlic coated tablets in peripheral arterial occlusive diseaseClin Investig.(1993 May)
    3. L-Carnitine - G Brevetti, M Chiariello, G Ferulano, A Policicchio, E Nevola, A Rossini, T Attisano, G Ambrosio, N Siliprandi, C AngeliniIncreases in walking distance in patients with peripheral vascular disease treated with L-carnitine: a double-blind, cross-over studyCirculation.(1988 Apr)
    4. Garlic - Jepson RG, Kleijnen J, Leng GCGarlic for peripheral arterial occlusive diseaseCochrane Database Syst Rev.(2013 Apr 30)
    5. L-Carnitine - G Brevetti, S Perna, C Sabbà, A Rossini, V Scotto di Uccio, E Berardi, L GodiSuperiority of L-propionylcarnitine vs L-carnitine in improving walking capacity in patients with peripheral vascular disease: an acute, intravenous, double-blind, cross-over studyEur Heart J.(1992 Feb)
    6. Cocoa Extract - Loffredo L, Perri L, Catasca E, Pignatelli P, Brancorsini M, Nocella C, De Falco E, Bartimoccia S, Frati G, Carnevale R, Violi FDark chocolate acutely improves walking autonomy in patients with peripheral artery diseaseJ Am Heart Assoc.(2014 Jul 2)