New Study Summaries publishedstudy summary
Prebiotics or probiotics for constipation-predominant irritable bowel syndrome?
Vitamin B9 may reduce cardiovascular disease risk factors in type 2 diabetes
How does the quality of a plant-based diet affect mortality risk?
The effects of a Mediterranean diet on people with type 2 diabetes
Is the effect of time-restricted eating on cardiometabolic health simply due to caloric restriction?
Prebiotic fiber for cognitive function, mood, and sleep
Diet vs. exercise for improving clinical outcomes in people with type 2 diabetes
New Study Summaries publishedstudy summary
Can carob improve sperm quality in men with infertility?
Ultraprocessed food consumption and childhood obesity
Blood glucose levels: Rye vs. herb-enriched multigrain bread
Associations between vitamin D deficiency and cardiometabolic risk factors in participants with systemic lupus erythematosus
Dietary patterns and insomnia symptoms
Probiotics may improve metabolic health in adults with prediabetes
Probiotics for improving cognition in mild cognitive impairment and Alzheimer’s disease
Butterbur - New page created
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We added a page for Butterbur with new Summary, Dosage, and FAQ sections. One existing FAQ was updated to note that several international societies do not recommend Butterbur for migraine due to the risk of liver damage.
New Study Summaries publishedstudy summary
Does acute supplementation with wild blueberry extract improve cognitive function in older adults?
The association between alcohol intake and sarcopenia risk
Probiotics as a treatment for dental implant diseases
Sunlight exposure and the risk of allergic conditions in children
Saturated fat and polyunsaturated fat promote similar lean mass gains during overfeeding
Coenzyme Q10 may improve endothelial function
Does higher adherence to a Mediterranean diet improve markers of antioxidant status in the context of nonalcoholic fatty liver disease?
New Study Summaries publishedstudy summary
Vitamin D may reduce the risk of bronchopulmonary dysplasia in preterm infants
Vegetarianism and long-term mental health trajectories
Is Ramadan fasting associated with changes in blood lipids, uric acid, or HbA1c in people with kidney disease?
Large intermittent doses of vitamin D don’t affect risk of fractures, falls, or mortality in older adults
Is a preworkout supplement better than caffeine alone for improving resistance exercise performance?
Is creatine useful for cyclists?
Is acetaminophen (Tylenol) use during pregnancy associated with an increased risk of neurodevelopmental conditions?
New Study Summaries publishedstudy summary
Lemon verbena for improving sleep
Acute caffeine intake increases muscle strength and endurance
Herbs for allergic rhinitis?
Muscles, bones, and veggies: Associations between dietary patterns and osteosarcopenia
Does date palm pollen improve sperm quality in male infertility?
How long should you fast to improve cardiometabolic health?
Is dairy intake associated with cognitive decline/dementia?
Memory & Focus - Updated to V3 and added new entries.
majorsupplement guide
- All entries have been updated to our new V3 evidence standards and have been reviewed again in light of the most recent evidence.
- We added Ginkgo bilba, Panax ginseng, and Rhodiola rosea
- The guide has been copyedited to improve writing quality
New Study Summaries publishedstudy summary
Spirulina for COVID-19
Carnitine improves blood lipids in people with type 2 diabetes
The effect of plant-based meat on cardiometabolic health
Malnutrition linked to worse health outcomes in older adults with hip fracture
A mitochondrial antioxidant improves endothelial function in adults, but baseline fitness level matters
Dietary CoQ10 and hypertension risk
Protein supplements and resistance training: What works best for older adults?
N-Acetylcysteine - New FAQ added
majorcontent
We added a new FAQ covering the current research on NAC in Parkinson's disease. Research is preliminary, but points to a potential benefit of intravenous NAC for improving dopamine functioning in the brain with a corresponding reduction in symptoms of Parkinson's disease.
5-HTP - Full page update
majorcontent
We updated the following FAQs:
What are 5-HTP's main benefits?: We added more details on the benefits of 5-HTP, as well as research limitations. Reducing symptoms of depression and promoting weight loss through appetite regulation remain the main potential benefits of 5-HTP. We removed sleep from this section due to unclear evidence of a benefit and potentially negative effects on sleep. Parkinson's disease, headache prevention, and fibromyalgia were added as areas of interest with a currently inconclusive and mixed evidence base.
What are 5-HTP's main drawbacks?: We added information about possible side effects with 5-HTP, the most common being nausea, abdominal pain, and diarrhea. We discussed the connection between 5-HTP and eosinophilia myalgia syndrome which was likely due to a toxic contaminant in the supplements and has not been observed in recent years.
Does 5-HTP affect sleep?: We added an FAQ to discuss the research on 5-HTP and sleep. Currently, no consistent benefit on sleep has been observed and some studies have reported increased rates of nightmares or reduced sleep duration.
Is tryptophan supplementation a suitable alternative to 5-HTP?: We added an FAQ to discuss whether tryptophan can be taken in place of 5-HTP. 5-HTP is a more reliable way of increasing serotonin levels than tryptophan because it crosses the blood-brain barrier more easily, requires less steps for serotonin synthesis, and has less alternative uses in the body.